Biotech Values

[AlpineBV_Miller]

There is another subtle difference with shorting in that losses on short sales require you to come up with more money. Losses on long position simply leave you with less money than you had.

Shorting a stock is inherently more risky. Always.

As far as options are concerned, I agree with you when it comes to buying calls. Selling calls and buying puts are transactions all biotech investors should work to become expers at because they can significantly add to annual performance.